Clinical Trials

The purpose of this study is to determine the occurrence of scarring of the heart (cardiac fibrosis) and inflammation in those with perinatally acquired Human Immunodeficiency Virus (HIV) infection compared to people not infected with HIV. The information learned from this research may help the investigator to better understand the link between cardiac fibrosis and cardiac dysfunction and inflammation in those with perinatally acquired HIV infection compared to the uninfected.

Do you have heart disease? This study is looking to improve the quality of heart CT scans by using new methods to create the images. You may be able to participate in the study if you are 18 years old or older, have heart disease, and have been told by your doctor that you need a CT scan. This study is taking place at the National Institutes of Health Clinical Center in Bethesda, Maryland.

Are you a woman with coronary microvascular dysfunction? In this clinical trial, researchers are studying coronary microvascular dysfunction, which occurs when there are problems in the small blood vessels in the heart. It frequently causes chest pain and is more common in women. The researchers want to learn how daily life and mental stress affect the heart. You may be able to participate if you are at least 45 years old, have gone through menopause, and are willing to undergo tests to measure your stress level. The study is taking place at locations in Atlanta, Georgia.