Clinical Trials

Are you a Hispanic adult with high blood pressure that is not well-controlled and an established patient at the Health Policy Research Institute? This study is looking at different ways to educate people with high blood pressure to help them remember to take their medicine correctly. Over 4 to 8 weeks, participants will have four educational sessins with a healthcare provider to learn about high blood pressure and blood pressure medicine, as well as lifestyle strategies to improve health and well-being. This study takes place in Irvine, California.

Are you an adult with sickle cell disease who’s recently had a vaso-occlusive episode? This study investigates better ways for emergency departments (EDs) to manage vaso-occlusive episodes, or pain crises, in people with sickle cell disease. This study is incorporating “Individualized Pain Plans” into patients’ electronic health records to allow for faster and more accurate treatment in the ED. To participate in this study, you must be between the ages of 18 and 45 and have sickle cell disease. You must also have had at least one visit to a participating ED in the past 90 days due to pain from a vaso-occlusive episode and at least one visit at the study site sickle cell disease clinic within the past 12 months. This study takes place in multiple locations in the United States.

Are you or your child between the ages of 3 and 21 and experiencing pain episodes? This study tests a treatment called arginine therapy for pain episodes in children with sickle cell disease. Researchers are investigating how safe and effective this treatment is, as well as how arginine is metabolized in the body and its effects on cells. To participate in this study, you or your child must have sickle cell disease and pain that requires medical attention. This study takes place in multiple locations in the United States.

This study is testing whether a medicine called metformin can help treat aortic aneurisms in the abdomen. The study will use imaging tests to examine whether metformin can help prevent these aortic aneurisms from getting bigger. To participate in this study, you must be 55 to 90 years old and diagnosed with an abdominal aortic aneurism. This study takes place in Stanford, California.

Are you between 65 and 85 years old and are a patient at Stanford? This study will evaluate the effect of an electronic health record (EHR) screening tool on rates of new noninvasive testing, diagnosis, and treatment of peripheral artery disease (PAD) over a 6-month period. The EHR-based screening tool will generate a group of patients at the highest risk of having undiagnosed PAD to participate in the study. To participate in this study, you must be between 65 and 85 years old, have at least 1 year of data with the Stanford EHR, and have no prior diagnosis of PAD. This study takes place in Palo Alto, California.

Are you an adult with asthma who is being treated with therapeutic proteins or is interested in trying this treatment? This study investigates the use of a treatment using therapeutic proteins in people with asthma and seeks to determine whether its use can lower inflammation in patients. To participate in this study, you must be between 18 and 80 years old. This study takes place in San Francisco, California.

Are you an adult currently being treated for rhinosinusitis (nasal inflammation) who would like to support research into the condition? This study is collecting blood, secretion, and tissue samples from people undergoing procedures to treat long-term rhinosinusitis. Rhinosinusitis, another term for nasal inflammation, is common in people who have asthma. To participate in this study, you must be between 18 and 80 years old. This study takes place in San Francisco, California.

Do you or your child have severe asthma that is not easily controlled by inhaled corticosteroids? This study evaluates the use of five different asthma medicines to treat adults and adolescents with severe asthma. To participate in this study, you or your child must be 12 years old or older. This study takes place in multiple locations across the United States.

Are you a woman 18 years old or older who has been diagnosed with LAM? This study is examining whether long-term treatment with medicine called sirolimus can stop lung damage in women who have LAM. This study takes place at multiple locations in the United States.

Do you or your child have symptoms of a serious lung disease but no diagnosis? This study aims to develop new ways to diagnose primary ciliary dyskinesia (PCD) and primary immune deficiency (PID), two conditions that can have similar symptoms. Researchers will combine information from genetic testing, lung imaging, and lung function tests to diagnose ant tell the difference between these two conditions. Participants in this study must be 5 to 45 years old. This study is taking place at multiple locations in the United States and in Canada.