Clinical Trials

The goal of this research is to assess the utility of smartphone-based progressive muscle relaxation (PMR) for the treatment of migraine and sleep.

The purpose of this project is to test sleep reactivity as an independent cause of Shift Work Disorder (SWD).

Do you have HIV and insomnia? This study is looking at whether insomnia increases pain and inflammation in people who have HIV. To participate in this study, you must be 18 to 85 years old and either be healthy or diagnosed with HIV, with or without insomnia. This study is located in Birmingham, Alabama.

Have you previously been prescribed opioid medicines? This study will find out whether waking up frequently during the night can affect the way your brain processes certain medicines. To participate in this study, you must be 18 to 48 years old, have a normal sleep cycle, and have previously taken opioid medicines to treat pain. This study is located in Baltimore, Maryland.

Are you or your child at least 13 years old and have sickle cell disease? In this stidy, researchers are trying to find out if a new medication improves the success of a blood stem cell transplant. People 13 years old or older who are eligible for a blood stem cell transplant to treat sickle cell disease may be able to participate. Healthy family members over age 13 who are matched to transplant recipients are also needed to donate blood for the study. This study is taking place at the National Institutes of Health Clinical Center in Bethesda, Maryland.

Are you a woman with coronary microvascular dysfunction? In this clinical trial, researchers are studying coronary microvascular dysfunction, which occurs when there are problems in the small blood vessels in the heart. It frequently causes chest pain and is more common in women. The researchers want to learn how daily life and mental stress affect the heart. You may be able to participate if you are at least 45 years old, have gone through menopause, and are willing to undergo tests to measure your stress level. The study is taking place at locations in Atlanta, Georgia.