Clinical Trials

Are you 18 or older, a patient in the PRISMA Health primary care clinics, and got a referral from your primary care provider for a physical activity program? Researchers are looking at how well a 12-week physical activity program works. You will need a referral from your primary care provider to join. The study is taking place in Greenville, South Carolina.

This is an observational - data and specimen collection study. There have been increasing reports of vaping-induced lung injury, including severe lung injury and rare cases of death. The mechanism by which vaping contributes to lung injury in susceptible persons is unknown, as is impact on chronic lung disease. The investigators aim to identify individuals with chronic electronic nicotine delivery device (ENDD) exposure and matched controls within our ongoing cohort of HIV+ and HIV-uninfected individuals, collect PFT data, bank respiratory and stool samples and collect clinical data for studies of clinical risk, inflammation, biomarkers, and the microbiome in the identification and modification of risk of progression to lung injury or chronic pulmonary disease.

The overall goal is to assess the potential of the radiotracer to track inflammatory cells in lung diseases.

Have you or your child been diagnosed with a blood disorder? If so, you (or they) may be able to participate in a clinical study where researchers are studying a type of infusion using cord blood. Participants can be of any age but must have a blood disorder diagnosed by their doctor. The study is taking place in locations in Alabama, Arizona, California, Colorado, Delaware, Florida, Georgia, Illinois, Indiana, Kentucky, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Nebraska, New York, Ohio, Oklahoma, Oregon, Pennsylvania, South Carolina, Tennessee, Texas, Virginia, Washington, Washington, D.C., West Virginia, and Wisconsin.

Do you or your child have an immunodeficiency, such as fewer T cells or NK cells? You can help researchers better understand how some types of immunodeficiencies are inherited. Participants in this study must be at least 6 months of age. This study is located at the NIH Clinical Center in Bethesda, Maryland.