Clinical Trials

Has your child been treated for an asthma attack with an oral corticosteroid medicine in the last 12 months? A study team will recruit 60 teens and young adults (between 12 and 21 years old) with persistent asthma who are at high risk for future exacerbation. This study examines the contribution of interleukin 1 beta (IL-1β), a protein that is involved in the inflammatory response, in asthma flare-ups. This study takes place in Chapel Hill, North Carolina.

Are you an adult with asthma, and do you want to help researchers understand how asthma may affect the brain health? This study is examining whether long-term asthma complications are associated with brain structure, function, or cognitive function. In people with asthma, allergens can induce airway inflammation, which activates several cell types that could negatively affect the brain over time. Results from this study may shed light on whether there is a connection between brain health and asthma. To participate in this study, you must be between 18 and 50 years old. This study takes place in Madison, Wisconsin.

Are you the parent or caregiver of a 12- to 15-year-old child with asthma who uses an inhaled corticosteroid to treat symptoms? This study is testing whether a mobile health tool, called AIM2ACT, can help adolescents and their caregivers manage symptoms of asthma. To participate in this study, you must be between 18 and 70 years old. This study takes place in Gainesville, Florida.

Are you an adult with moderate to severe asthma? Researchers are testing whether inhaling hypertonic saline (a saline solution with more salt) can help move mucus out of the lungs in people with asthma. To participate in this study, you must be between 18 and 60 years old and vaccinated against COVID-19. This study takes place in New York, New York.

Are you an adult with severe asthma who plans to have bronchial thermoplasty treatment? This study is using a new imaging technique, called optical coherence tomography, to examine the airways in people with asthma before and after a treatment called bronchial thermoplasty. This treatment is minimally invasive and reduces asthma symptoms by using heat to shrink smooth muscle within the lungs. To participate in this survey, you must be between 18 and 60 years old. This study takes place in Boston, Massachusetts.

Are you an adult with asthma who is being treated with therapeutic proteins or is interested in trying this treatment? This study investigates the use of a treatment using therapeutic proteins in people with asthma and seeks to determine whether its use can lower inflammation in patients. To participate in this study, you must be between 18 and 80 years old. This study takes place in San Francisco, California.

Are you an adult currently being treated for rhinosinusitis (nasal inflammation) who would like to support research into the condition? This study is collecting blood, secretion, and tissue samples from people undergoing procedures to treat long-term rhinosinusitis. Rhinosinusitis, another term for nasal inflammation, is common in people who have asthma. To participate in this study, you must be between 18 and 80 years old. This study takes place in San Francisco, California.

Do you or your child have severe asthma that is not easily controlled by inhaled corticosteroids? This study evaluates the use of five different asthma medicines to treat adults and adolescents with severe asthma. To participate in this study, you or your child must be 12 years old or older. This study takes place in multiple locations across the United States.

Are you an adult who has participated in one or more HIV Lung Research Group studies and would like to support better treatment options for people living with HIV and COPD? This study aims to find out whether microbes in the lungs or gut raise the risk of COPD in people living with HIV. Results from this study will help improve COPD treatment options in the HIV+ population. To participate in this study, you must be 18 to 80 years old. This study takes place in Pittsburgh, Pennsylvania.

Are you interested in supporting research into safe and effective flu prevention for people with COPD? This study is testing whether the nasal spray flu vaccine is safe and effective in people who have COPD. To participate in this study, you must be at least 40 years old and either healthy or diagnosed with COPD. This study takes place in Chapel Hill, North Carolina.